Myocardial Hypertrophy, Matrix Expansion, and Focal Scar
نویسندگان
چکیده
منابع مشابه
Myocardial infarct expansion and matrix metalloproteinase inhibition.
BACKGROUND A potential mechanism for left ventricular (LV) remodeling after myocardial infarction (MI) is activation of the matrix metalloproteinases (MMPs). This study examined the effects of MMP inhibition (MMPi) on regional LV geometry and MMP levels after MI. METHODS AND RESULTS In pigs instrumented with radiopaque markers to measure regional myocardial geometry, MI was created by ligatin...
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Objective(s):To examine the expressions of CD11a, CD11b, and CD11c integrins in the myocardial tissues of rats with isoproterenol-induced myocardial hypertrophy. This study also provided morphological data to investigate the signal transduction mechanisms of myocardial hypertrophy and reverse it. Materials and Methods: A myocardial hypertrophy model was established by subcutaneously injecting i...
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Methods Under IRB approved protocol a total of 82 HCM patients underwent LGE CMR images using a 2D PSIR TurboFLASH protocol after administration of 0.2 mmol of gadopentetate dimeglumine per kilogram of body weight. The presence of LGE was assessed using automated software: percentage of scar and maximal wall thickness were calculated. Percentage of scar was compared between patients with mWT <2...
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Methods By using a 1.5T scanner have 68 patients with a high likelihood of coronary artery disease been included. The following MRI protocol was used: cine SSFP, single slice multiphase Displacement ENcoding with Stimulated Echoes (DENSE) during breath holding, perfusion during adenosine stress and at rest and late gadolinium enhancement. Ejection fraction was calculated from the short axis cin...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Imaging
سال: 2018
ISSN: 1941-9651,1942-0080
DOI: 10.1161/circimaging.118.007975